File Name: difference between acute and chronic leukemia .zip
- Acute myeloid leukaemia (AML)
- Acute and Chronic Leukemia: What Are the Differences?
- Types of leukemia
- What Is Chronic Myeloid Leukemia?
Leukaemia is the eleventh commonest UK cancer. The four main subtypes have different clinical profiles, particularly between chronic and acute types. To identify the symptom profiles of chronic and acute leukaemia in adults in primary care.
Acute myeloid leukaemia (AML)
Leukemia is classified by the type of white blood cells affected and by how quickly the disease progresses. Lymphocytic leukemia also known as lymphoid or lymphoblastic leukemia develops in the white blood cells called lymphocytes in the bone marrow. Myeloid also known as myelogenous leukemia may also start in white blood cells other than lymphocytes, as well as red blood cells and platelets. Acute leukemia is rapidly progressing and results in the accumulation of immature, functionless blood cells in the bone marrow. Chronic leukemia progresses more slowly and results in the accumulation of relatively mature, but still abnormal, white blood cells. The leukemia cells are carried in the bloodstream to other organs and tissues, including the brain, liver, lymph nodes and testes, where they continue to grow and divide.
Leukemia is a cancer of the blood. It forms when blood cells in the bone marrow malfunction and form cancerous cells. The cancerous blood cells then overrun the normal blood cells. The cancerous cells can also invade the spleen, liver, and other organs. Chronic leukemia is a slow-growing leukemia. Acute leukemia is a fast-growing leukemia that progresses quickly without treatment.
The Mario Lemieux Center for Blood Cancers offers personalized treatments for patients with all types of blood cancer. The Gumberg Family Resource Center provides educational resources for patients and caregivers. UPMC Hillman Cancer Center offers patients access to the latest advances in cancer prevention, detection, diagnosis, and treatment through cancer clinical trials. For general information or questions, call Leukemia is the result of the rapid overproduction of abnormal white blood cells.
Acute and Chronic Leukemia: What Are the Differences?
It starts when immature white blood cells called blasts become cancerous. These abnormal blast cells are known as leukaemia cells. They multiply quickly and continue to divide but never mature into normal cells. This increases the risk of infections. When the bone marrow fills with leukaemia cells, there is little room for normal red blood cells and platelets. This can cause fatigue, bleeding problems and other health issues.
forms of the disease progress rapidly and require prompt treatment. They target immature cells, causing symptoms to appear quickly.
Types of leukemia
Leukemia , also spelled leukaemia , is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. The exact cause of leukemia is unknown. Treatment may involve some combination of chemotherapy , radiation therapy , targeted therapy , and bone marrow transplant , in addition to supportive care and palliative care as needed. Outcomes have improved in the developed world.
What Is Chronic Myeloid Leukemia?
Leukemia is a malignant condition involving the excess production of immature or abnormal leukocytes, which eventually suppresses the production of normal blood cells and results in symptoms related to cytopenias. Malignant transformation usually occurs at the pluripotent stem cell level, although it sometimes involves a committed stem cell with more limited capacity for self-renewal. Abnormal proliferation, clonal expansion, aberrant differentiation, and diminished apoptosis programmed cell death lead to replacement of normal blood elements with malignant cells.
Patient information : See related handout on leukemia , written by the authors of this article. Leukemia is a clonal proliferation of hematopoietic stem cells in the bone marrow. The four broad subtypes most likely to be encountered by primary care physicians are acute lymphoblastic, acute myelogenous, chronic lymphocytic, and chronic myelogenous. Acute lymphoblastic leukemia occurs more often in children, whereas the other subtypes are more common in adults.
The terms acute and chronic are based on how quickly the disease progresses and the maturity of the affected cells. Acute forms of the disease progress rapidly and require prompt treatment. They target immature cells, causing symptoms to appear quickly. Chronic forms of leukemia, on the other hand, target more mature cells and develop over long periods of time. It is not unusual in chronic cases for symptoms to take a long time to even appear.
Cancer starts when cells in the body start to grow out of control. Cells in nearly any part of the body can become cancer, and can spread to other parts of the body. To learn more about how cancers start and spread, see What Is Cancer? Chronic myeloid leukemia CML is also known as chronic myelogenous leukemia. It's a type of cancer that starts in certain blood-forming cells of the bone marrow.
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